Euphorbia is a very large and diverse genus of flowering plants, commonly called spurge, in the family Euphorbiaceae. "Euphorbia" is sometimes used in ordinary English to collectively refer to all members of Euphorbiaceae (in deference to the type genus), not just to members of the genus.

Euphorbias range from tiny annual plants to large and long-lived trees. with perhaps the tallest being Euphorbia ampliphylla at 98 feet (thirty meters) or more. The genus has roughly 2,000 members, making it one of the largest genera of flowering plants. It also has one of the largest ranges of chromosome counts, along with Rumex and Senecio. Euphorbia antiquorum is the type species for the genus Euphorbia. It was first described by Carl Linnaeus in 1753 in Species Plantarum.

Some euphorbias are widely available commercially, such as poinsettias at Christmas. Some are commonly cultivated as ornamentals, or collected and highly valued for the aesthetic appearance of their unique floral structures, such as the crown of thorns plant (Euphorbia milii). Succulent euphorbias from the deserts of Southern Africa and Madagascar have evolved physical characteristics and forms similar to cacti of North and South America, so they are often incorrectly referred to as cacti. Some are used as ornamentals in landscaping, because of beautiful or striking overall forms, and drought and heat tolerance.

Euphorbia all share the feature of having a poisonous, latex-like sap and unique floral structures. When viewed as a whole, the head of flowers looks like a single flower (a pseudanthium). It has a unique kind of pseudanthium, called a cyathium, where each flower in the head is reduced to its barest essential part needed for sexual reproduction. The individual flowers are either male or female, with the male flowers reduced to only the stamen, and the females to the pistil. These flowers have no sepals, petals, or other parts that are typical of flowers in other kinds of plants. Structures supporting the flower head and other structures underneath have evolved to attract pollinators with nectar, and with shapes and colors that function in a way petals and other flower parts do in other flowers. It is the only genus of plants that has all three kinds of photosynthesis, CAM, C3 and C4.